7LOV
Crystal structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP and noeuromycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Toxin B | polymer | 552 | 64313.8 | 2 | UniProt (P18177) | Clostridioides difficile (Peptoclostridium difficile) | |
| 2 | C, I (A, B) | (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL | non-polymer | 163.2 | 2 | Chemie (NOY) | |||
| 3 | D, J (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (1158) PubChem (6031) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 4 | E, F, G, K, L (A, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) PubChem (753) | |||
| 5 | H, M (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 545 (UniProt: P18177)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Leu 544 | Gly 544 | conflict |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128627.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1705.0 | |
| All* | Total formula weight | 130332.7 |
