7LOU
Crystal structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP and isofagomine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glucosyltransferase TcdB | polymer | 552 | 64313.8 | 2 | UniProt (P18177) Pfam (PF12918) Pfam (PF12919) In PDB | Clostridioides difficile (Peptoclostridium difficile) | |
2 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 19 | Chemie (EDO) | |||
3 | A, B | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
4 | A, B | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE | non-polymer | 147.2 | 2 | Chemie (IFM) | |||
5 | B, A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
6 | water | water | 18.0 | 487 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 543 (UniProt: P18177)
PDB | External Database | Details |
---|---|---|
Met 0 | - | expression tag |
Gly 1 | - | expression tag |
Leu 544 | - | expression tag |
Glu 545 | - | expression tag |
His 546 | - | expression tag |
His 547 | - | expression tag |
His 548 | - | expression tag |
His 549 | - | expression tag |
His 550 | - | expression tag |
His 551 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 128627.7 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 2391.8 | |
All* | Total formula weight | 131019.5 |