7LOP
Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV05-163 and CR3022
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | W, B | CR3022 Fab heavy chain | polymer | 222 | 23455.4 | 2 | Homo sapiens | ||
2 | V, C | CR3022 Fab light chain | polymer | 221 | 24377.0 | 2 | Homo sapiens | ||
3 | Z, A | Spike protein S1 | polymer | 231 | 26095.3 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
4 | X, H | CV05-163 Fab heavy chain | polymer | 227 | 24227.3 | 2 | Homo sapiens | ||
5 | Y, L | CV05-163 Fab light chain | polymer | 216 | 23521.1 | 2 | Homo sapiens | ||
6 | Z, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
7 | water | water | 18.0 | 1237 | Chemie (HOH) |
Sequence modifications
Z, A: 319 - 541 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Ser 542 | - | expression tag |
Gly 543 | - | expression tag |
His 544 | - | expression tag |
His 545 | - | expression tag |
His 546 | - | expression tag |
His 547 | - | expression tag |
His 548 | - | expression tag |
His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 243352.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 243794.7 |