7LO4
SARS-CoV-2 spike receptor-binding domain with a G485R mutation in complex with human ACE2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Processed angiotensin-converting enzyme 2 | polymer | 596 | 69038.6 | 1 | UniProt (Q9BYF1) Pfam (PF01401) | Homo sapiens (Human) | |
| 2 | B (B) | Spike protein S1 | polymer | 200 | 22562.3 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 4 | D, E, F, K (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | G, H, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | J (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
B: 333 - 530 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Arg 485 | Gly 485 | engineered mutation |
| Glu 531 | - | expression tag |
| Asn 532 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91600.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1136.4 | |
| All* | Total formula weight | 93307.9 |
