7LNL
Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed imipenem
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Carbapenem-hydrolyzing beta-lactamase KPC | polymer | 268 | 28314.9 | 2 | UniProt (Q9F663) Pfam (PF00144) Pfam (PF13354) In PDB | Klebsiella pneumoniae | Carbapenem-hydrolyzing beta-lactamase KPC-1 |
2 | A, B | (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid | non-polymer | 317.4 | 2 | Chemie (8YF) | |||
3 | water | water | 18.0 | 581 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 291 (UniProt: Q9F663)
PDB | External Database | Details |
---|---|---|
Gly 70 | Ser 69 | engineered mutation |
Pro 215 | Thr 214 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56629.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 634.7 | |
All* | Total formula weight | 57264.5 |