7LN6
Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 2, Open State)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Transitional endoplasmic reticulum ATPase | polymer | 806 | 89493.9 | 6 | UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (Human) | TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP |
| 2 | G | polyubiquitinated Ub-Eos | polymer | 23 | 1975.4 | 1 | Mus musculus (Mouse) | ||
| 3 | A, B, C, F | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 5 | Chemie (ADP) | |||
| 4 | B, D, E, F | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 7 | Chemie (ATP) | |||
| 5 | B, C, D, E, F | MAGNESIUM ION | non-polymer | 24.3 | 7 | Chemie (MG) |
Sequence modifications
A, B, C, D, E, F: 1 - 806 (UniProt: P55072)
| PDB | External Database | Details |
|---|---|---|
| Glu 232 | Ala 232 | engineered mutation |
| Gln 578 | Glu 578 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 538938.5 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 5856.4 | |
| All* | Total formula weight | 544794.9 |
