7LMC
Structure of SARS CoV-2 main protease shows simultaneous processing of its N- and C-terminii
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (E, F) | Non-structural protein 4 peptide | polymer | 6 | 617.7 | 2 | UniProt (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | nsp4 |
| 2 | B, C, E, F (A, B, C, D) | 3C-like proteinase | polymer | 306 | 33793.5 | 4 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
Sequence modifications
A, B, C, D: 1 - 306 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 145 | Cys 3408 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 136409.3 | |
| All* | Total formula weight | 136409.3 |
