7LM4
The crystal structure of the I38T mutant PA Endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ000988503
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polymerase acidic protein | polymer | 197 | 23136.3 | 1 | UniProt (C3W5S0) In PDB | Influenza A virus (strain swl A/California/04/2009 H1N1) | RNA-directed RNA polymerase subunit P2 |
2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
3 | A | 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2-(2-methylphenyl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide | non-polymer | 395.4 | 1 | Chemie (Y5V) | |||
4 | A | Hexa Vinylpyrrolidone K15 | non-polymer | 668.9 | 1 | Chemie (QQ4) | |||
5 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
6 | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 1 - 196 (UniProt: C3W5S0)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Thr 38 | Ile 38 | engineered mutation |
- | Phe 51 | deletion |
- | His 52 | deletion |
- | Phe 53 | deletion |
- | Ile 54 | deletion |
- | Asp 55 | deletion |
- | Glu 56 | deletion |
- | Arg 57 | deletion |
- | Gly 58 | deletion |
- | Glu 59 | deletion |
- | Ser 60 | deletion |
- | Ile 61 | deletion |
- | Ile 62 | deletion |
- | Val 63 | deletion |
- | Glu 64 | deletion |
- | Ser 65 | deletion |
- | Gly 66 | deletion |
- | Asp 67 | deletion |
- | Pro 68 | deletion |
- | Asn 69 | deletion |
Gly 51 | Ala 70 | conflict |
Gly 52 | Leu 71 | conflict |
Ser 53 | Leu 72 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23136.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1462.3 | |
All* | Total formula weight | 24598.6 |