7LLB
Crystal structure of KPC-2 S70G/T215P mutant with hydrolyzed meropenem
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Carbapenem-hydrolyzing beta-lactamase KPC | polymer | 264 | 27958.5 | 2 | UniProt (Q9F663) | Klebsiella pneumoniae | Carbapenem-hydrolyzing beta-lactamase KPC-1 |
| 2 | C, D (A, B) | (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid | non-polymer | 401.5 | 2 | Chemie (8YL) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 560 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 291 (UniProt: Q9F663)
| PDB | External Database | Details |
|---|---|---|
| Gly 70 | Ser 69 | engineered mutation |
| Pro 215 | Thr 214 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55917.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 803.0 | |
| All* | Total formula weight | 56719.9 |
