7LKK

Crystal structure of Helicobacter pylori aminofutalosine deaminase (AFLDA) in complex with Methylthio-coformycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Aminofutalosine deaminase	polymer	423	47520.1	4	UniProt (Q9ZMG8) Pfam (PF01979)	Helicobacter pylori	AFLDA
2	E, K, O, S (A, B, C, D)	FE (III) ION	non-polymer		55.8	4	Chemie (FE)
3	F, G, H, I, L... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	13	Chemie (EDO)
4	J, N, R, Y (A, B, C, D)	(8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol	non-polymer		314.4	4	Chemie (MCF)
5	AA, BA, CA, Z (B, C, D, A)	water	water		18.0	971	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 409 (UniProt: Q9ZMG8)

PDB	External Database	Details
Met -13	-	initiating methionine
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	190080.5
Non-Polymers*	Number of molecules	21
	Total formula weight	2287.7
All*	Total formula weight	192368.2

*Water molecules are not included.