7LJU
Porcine Dihydropyrimidine Dehydrogenase (DPD) crosslinked with 5-Ethynyluracil (5EU)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, D, B) | Dihydropyrimidine dehydrogenase [NADP(+)] | polymer | 1025 | 111603.3 | 4 | UniProt (Q28943) Pfam (PF14691) Pfam (PF07992) Pfam (PF01180) Pfam (PF14697) | Sus scrofa (Pig) | DPD,Dihydrothymine dehydrogenase,Dihydrouracil dehydrogenase |
| 2 | CA, DA, E, EA, F... (B, A, C, D) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 16 | Chemie (SF4) | |||
| 3 | GA, I, Q, Y (B, A, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 4 | J, JA, T, Z (A, B, C, D) | 5-ethynylpyrimidine-2,4(1H,3H)-dione | non-polymer | 136.1 | 4 | Chemie (Y3G) | |||
| 5 | AA, HA, K, R (D, B, A, C) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 4 | Chemie (NAP) | |||
| 6 | BA, IA, L, S (D, B, A, C) | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL | non-polymer | 458.4 | 4 | Chemie (FNR) | |||
| 7 | KA, LA, MA, NA (A, C, D, B) | water | water | 18.0 | 3389 | Chemie (HOH) |
Sequence modifications
A, C, D, B: 1 - 1025 (UniProt: Q28943)
| PDB | External Database | Details |
|---|---|---|
| Asp 60 | Gly 60 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 446413.4 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 14119.9 | |
| All* | Total formula weight | 460533.3 |
