7LJS
Porcine Dihydropyrimidine dehydrogenase (DPD) complexed with 5-Ethynyluracil (5EU) - Open Form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Dihydropyrimidine dehydrogenase [NADP(+)] | polymer | 1025 | 111603.3 | 4 | UniProt (Q28943) Pfam (PF14691) Pfam (PF07992) Pfam (PF01180) Pfam (PF14697) | Sus scrofa (Pig) | DPD,Dihydrothymine dehydrogenase,Dihydrouracil dehydrogenase |
| 2 | AA, BA, CA, E, F... (D, A, B, C) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 16 | Chemie (SF4) | |||
| 3 | DA, I, P, W (D, A, B, C) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 4 | Chemie (FMN) | |||
| 4 | EA, J, Q, X (D, A, B, C) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 5 | FA, K, R, Y (D, A, B, C) | 5-ethynylpyrimidine-2,4(1H,3H)-dione | non-polymer | 136.1 | 4 | Chemie (Y3G) | |||
| 6 | GA, HA, IA, JA (A, B, C, D) | water | water | 18.0 | 2171 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 1025 (UniProt: Q28943)
| PDB | External Database | Details |
|---|---|---|
| Asp 60 | Gly 60 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 446413.4 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 11138.2 | |
| All* | Total formula weight | 457551.6 |
