7LHU

Crystal structure of adenosine-5'-phosphosulfate reductase from Mycobacterium tuberculosis in a complex with product AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Phosphoadenosine phosphosulfate reductase	polymer	262	28525.1	2	UniProt (A5U586) Pfam (PF01507) UniProt (by SIFTS) (P9WIK3)	Mycobacterium tuberculosis	3'-phosphoadenylylsulfate reductase,PAPS reductase,thioredoxin dependent,PAPS sulfotransferase,PAdoPS reductase, adenosine-5'-phosphosulfate reductase
2	C, F (A, B)	IRON/SULFUR CLUSTER	non-polymer		351.6	2	Chemie (SF4)
3	D, G (A, B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES) PubChem (4478249)
4	E, H (A, B)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	2	Chemie (AMP) PubChem (224) PubChem (34768) PubChem (83862) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (5316444) PubChem (5742864) PubChem (12163610) PubChem (12358355) PubChem (16397049) PubChem (16760266) PubChem (40467049) PubChem (40469468) PubChem (44348067) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (46875232) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (92144436) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (12358354) PubChem (122197642) PubChem (162290139) PubChem (162946266) PubChem (171699505)
5	I, J (A, B)	water	water		18.0	7	Chemie (HOH)

Sequence modifications

A, B: 1 - 254 (UniProt: A5U586)

PDB	External Database	Details
Leu 255	-	expression tag
Glu 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag
His 262	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57050.1
Non-Polymers*	Number of molecules	6
	Total formula weight	1788.2
All*	Total formula weight	58838.3

*Water molecules are not included.