7LHM
Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retinol-binding protein 2 | polymer | 133 | 15574.6 | 2 | UniProt (P50120) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinol-binding protein II,CRBP-II |
| 2 | C, F (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | D, G (A, B) | RETINAL | non-polymer | 284.4 | 2 | Chemie (RET) | |||
| 4 | E, H (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 133 (UniProt: P50120)
| PDB | External Database | Details |
|---|---|---|
| Ala 4 | Gln 5 | engineered mutation |
| Trp 19 | Tyr 20 | engineered mutation |
| Leu 29 | Thr 30 | engineered mutation |
| Leu 38 | Gln 39 | engineered mutation |
| Leu 40 | Lys 41 | engineered mutation |
| Val 51 | Thr 52 | engineered mutation |
| Cys 53 | Thr 54 | engineered mutation |
| Trp 58 | Arg 59 | engineered mutation |
| Lys 108 | Gln 109 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31149.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 871.1 | |
| All* | Total formula weight | 32020.4 |
