7LFT
Cryo-EM structure of human Apo CNGA1 channel in K+/Ca2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | cGMP-gated cation channel alpha-1 | polymer | 560 | 64650.4 | 4 | UniProt (P29973) Pfam (PF00520) Pfam (PF00027) Pfam (PF16526) In PDB | Homo sapiens (Human) | Cyclic nucleotide-gated cation channel 1,Cyclic nucleotide-gated channel alpha-1,CNG1,Cyclic nucleotide-gated channel,photoreceptor,Rod photoreceptor cGMP-gated channel subunit alpha |
| 2 | A, D, B, C | CHOLESTEROL | non-polymer | 386.7 | 8 | Chemie (CLR) | |||
| 3 | C, A, D, B | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 758.1 | 24 | Chemie (CPL) | |||
| 4 | A | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 5 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 144 - 690 (UniProt: P29973)
| PDB | External Database | Details |
|---|---|---|
| Met 131 | - | initiating methionine |
| Asp 132 | - | expression tag |
| Tyr 133 | - | expression tag |
| Lys 134 | - | expression tag |
| Asp 135 | - | expression tag |
| Asp 136 | - | expression tag |
| Asp 137 | - | expression tag |
| Asp 138 | - | expression tag |
| Lys 139 | - | expression tag |
| Gly 140 | - | expression tag |
| Gly 141 | - | expression tag |
| Ser 142 | - | expression tag |
| Ala 143 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 258601.7 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 21404.0 | |
| All* | Total formula weight | 280005.7 |
