7LE7
HIV-1 Protease WT (NL4-3) in Complex with GS-8374
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Protease | polymer | 99 | 10831.8 | 2 | UniProt (Q8ULI9) Pfam (PF00077) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 | |
| 2 | B, A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A | DIETHYL ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONATE | non-polymer | 728.8 | 1 | Chemie (KGQ) | |||
| 4 | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: Q8ULI9)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21663.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1113.0 | |
| All* | Total formula weight | 22776.7 |
