7LDE

native AMPA receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Glutamate receptor 1	polymer	907	101679.0	2	UniProt (P23818) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Mus musculus (Mouse)	GluR-1,AMPA-selective glutamate receptor 1,GluR-A,GluR-K1,Glutamate receptor ionotropic,AMPA 1,GluA1
2	B, D	Glutamate receptor	polymer	883	98899.9	2	UniProt (G5E8H1) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) UniProt (by SIFTS) (P23819) In PDB	Mus musculus (Mouse)
3	E, F	Protein cornichon homolog 2	polymer	160	18948.4	2	UniProt (O35089) Pfam (PF03311) In PDB	Mus musculus (Mouse)	CNIH-2,Cornichon family AMPA receptor auxiliary protein 2,Cornichon-like protein
4	G, H	Voltage-dependent calcium channel gamma-8 subunit	polymer	423	43502.9	2	UniProt (Q8VHW2) Pfam (PF00822) In PDB	Mus musculus (Mouse)	Neuronal voltage-gated calcium channel gamma-8 subunit,Transmembrane AMPAR regulatory protein gamma-8,TARP gamma-8
5	I, L	11B8 scFv	polymer	257	27511.5	2		Mus musculus
6	J, M	15F1 Fab light chain	polymer	225	25111.7	2		Mus musculus
7	K, N	15F1 Fab heavy chain	polymer	262	27975.4	2		Mus musculus
8	O, P, Q, R, S	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
9	B, C, A, D	{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid	non-polymer		409.3	4	Chemie (ZK1)
10	C, A	HEXADECANE	non-polymer		226.4	2	Chemie (R16)
11	B, G, C, H, D...	N-OCTANE	non-polymer		114.2	6	Chemie (OCT)
12	A, C	HEPTANE	non-polymer		100.2	4	Chemie (HP6)
13	F, G, H, C, A...	DECANE	non-polymer		142.3	6	Chemie (D10)
14	B, C, D, A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)
15	B, G, H, D	DODECANE	non-polymer		170.3	6	Chemie (D12)
16	F, B, G, H, D...	TETRADECANE	non-polymer		198.4	6	Chemie (C14)
17	B, D	nonane	non-polymer		128.3	4	Chemie (DD9)
18	G, H	6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol	non-polymer		328.7	2	Chemie (XVD)

Sequence modifications

B, D: -20 - 862 (UniProt: G5E8H1)

PDB	External Database	Details
Arg 586	Gln 607	variant

Contents of the asymmetric unit

Polymers	Number of chains	14
	Total formula weight	687257.7
Branched	Number of molecules	5
	Total formula weight	2122.0
Non-Polymers*	Number of molecules	47
	Total formula weight	8960.9
All*	Total formula weight	698340.6

*Water molecules are not included.