7LD1
Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1121 | 124111.4 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | S glycoprotein,E2,Peplomer protein |
| 2 | D, F, H (M, P, H) | DH1047 heavy chain | polymer | 232 | 24834.7 | 3 | Homo sapiens (Human) | ||
| 3 | E, G, I (N, O, L) | DH1047 light chain | polymer | 220 | 24398.0 | 3 | Homo sapiens (Human) | ||
| 4 | J, L, M, N, O... (D, F, G, I, J...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 13 | In PDB GlyTouCan (G15407YE) | |||
| 5 | K, Q (E, Q) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | AA, BA, CA, DA, EA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 24 | Chemie (NAG) |
Sequence modifications
A, B, C: 27 - 1147 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 470 | Thr 470 | conflict |
| Ala 471 | Glu 471 | conflict |
| Tyr 486 | Phe 486 | conflict |
| Glu 607 | Gln 607 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 520032.4 | |
| Branched | Number of molecules | 15 |
| Total formula weight | 8473.8 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 5309.0 | |
| All* | Total formula weight | 533815.2 |
