7LBT

Crystal structure of the second bromodomain (BD2) of human BRD3 bound to ERK5-IN-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Bromodomain-containing protein 3	polymer	111	13089.1	4	UniProt (Q15059) Pfam (PF00439) In PDB	Homo sapiens (Human)	RING3-like protein
2	A, B, C, D	11-cyclopentyl-2-({2-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]phenyl}amino)-5-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one	non-polymer		638.8	4	Chemie (VYJ)
3		water	water		18.0	78	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	52356.5
Non-Polymers*	Number of molecules	4
	Total formula weight	2555.2
All*	Total formula weight	54911.7

*Water molecules are not included.