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7LBK

Crystal structure of human Survivin bound to histone H3 T3phK4me3 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(B, A)
Baculoviral IAP repeat-containing protein 5polymer14616826.12UniProt (O15392)
Pfam (PF00653)
Homo sapiens (Human)Apoptosis inhibitor 4,Apoptosis inhibitor survivin
2B, D
(D, C)
histone H3 T3phK4me3 peptidepolymer121430.52UniProt (P68431)Homo sapiensHistone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l
3E, F
(B, A)
ZINC IONnon-polymer65.42Chemie (ZN)
4G, H
(B, A)
waterwater18.034Chemie (HOH)
Sequence modifications
B, A: 1 - 142 (UniProt: O15392)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
His -1-expression tag
Glu 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight36513.3
Non-Polymers*Number of molecules2
Total formula weight130.8
All*Total formula weight36644.2
*Water molecules are not included.

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PDB entries from 2025-07-09

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