7LBD

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59K mutant with pyruvate bound in the active site in C2221 space group

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34176.3	6	UniProt (Q9PPB4) Pfam (PF00701) In PDB	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	A, B, F, C	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3	C, D, A, E, B...	1,2-ETHANEDIOL	non-polymer		62.1	16	Chemie (EDO)
4	C, D, A, E, B	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
5	C, D, A, E	ACETATE ION	non-polymer		59.0	10	Chemie (ACT)
6	F, C, D, A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	9	Chemie (PEG)
7		water	water		18.0	774	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Lys 59	His 59	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	205057.8
Non-Polymers*	Number of molecules	47
	Total formula weight	3585.5
All*	Total formula weight	208643.2

*Water molecules are not included.