7LB1
Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-585
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription initiation factor TFIID subunit 1 | polymer | 265 | 30968.3 | 1 | UniProt (P21675) Pfam (PF00439) | Homo sapiens (Human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250 |
| 2 | B, C, D, E, F... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 3 | K (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | U (A) | 5-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}isoquinoline | non-polymer | 423.5 | 1 | Chemie (XWV) | |||
| 5 | V (A) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A: 1373 - 1635 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Ser 1371 | - | expression tag |
| Met 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30968.3 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1646.9 | |
| All* | Total formula weight | 32615.1 |
