7LAW

crystal structure of GITR complex with GITR-L

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tumor necrosis factor ligand superfamily member 18	polymer	128	14515.6	2	UniProt (Q9UNG2) In PDB	Homo sapiens (Human)	Activation-inducible TNF-related ligand,AITRL,Glucocorticoid-induced TNF-related ligand,hGITRL
2	R, S	Tumor necrosis factor receptor superfamily member 18	polymer	147	15866.8	2	UniProt (Q9Y5U5) In PDB	Homo sapiens (Human)	Activation-inducible TNFR family receptor,Glucocorticoid-induced TNFR-related protein
3	A, B, R, S	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
4		water	water		18.0	48	Chemie (HOH)

Sequence modifications

R, S: 26 - 161 (UniProt: Q9Y5U5)

PDB	External Database	Details
Ala 162	-	expression tag
Ala 163	-	expression tag
Ala 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag
His 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	60764.7
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	61649.6

*Water molecules are not included.