7LAK
Crystal structure of the first bromodomain (BD1) of human BRD2 bound to volasertib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 2 | polymer | 122 | 14471.9 | 1 | UniProt (U3KQA6) Pfam (PF00439) UniProt (by SIFTS) (P25440) | Homo sapiens (Human) | |
| 2 | B (A) | N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide | non-polymer | 618.8 | 1 | Chemie (IBI) | |||
| 3 | C (A) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14471.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 618.8 | |
| All* | Total formula weight | 15090.7 |
