7L9Y
Human PARP14 (ARTD8), catalytic fragment in complex with RBN012042
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein mono-ADP-ribosyltransferase PARP14 | polymer | 194 | 22172.6 | 4 | UniProt (Q460N5) Pfam (PF00644) | Homo sapiens (Human) | ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2,Poly [ADP-ribose] polymerase 14,PARP-14 |
| 2 | E, I, M, O (A, B, C, D) | 7-(cyclopentylamino)-5-fluoro-2-{[(piperidin-4-yl)sulfanyl]methyl}quinazolin-4(3H)-one | non-polymer | 376.5 | 4 | Chemie (XRM) | |||
| 3 | F, G, J, N, P (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 4 | H, K, L, Q (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | R, S, T, U (A, B, C, D) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1611 - 1801 (UniProt: Q460N5)
| PDB | External Database | Details |
|---|---|---|
| Ser 1608 | - | expression tag |
| Asn 1609 | - | expression tag |
| Ala 1610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88690.3 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1931.5 | |
| All* | Total formula weight | 90621.8 |
