7L70
The eukaryotic translation initiation factor 2B from Homo sapiens in its apo form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Translation initiation factor eIF-2B subunit epsilon | polymer | 721 | 80452.6 | 2 | UniProt (Q13144) Pfam (PF02020) In PDB | Homo sapiens (Human) | eIF-2B GDP-GTP exchange factor subunit epsilon |
2 | C, D | Translation initiation factor eIF-2B subunit beta | polymer | 368 | 41008.6 | 2 | UniProt (P49770) Pfam (PF01008) In PDB | Homo sapiens (Human) | S20I15,S20III15,eIF-2B GDP-GTP exchange factor subunit beta |
3 | E, F | Translation initiation factor eIF-2B subunit delta | polymer | 523 | 57640.2 | 2 | UniProt (Q9UI10) Pfam (PF01008) In PDB | Homo sapiens (Human) | eIF-2B GDP-GTP exchange factor subunit delta |
4 | G, H | Translation initiation factor eIF-2B subunit alpha | polymer | 322 | 35723.2 | 2 | UniProt (Q14232) Pfam (PF01008) In PDB | Homo sapiens (Human) | eIF-2B GDP-GTP exchange factor subunit alpha |
5 | I, J | Translation initiation factor eIF-2B subunit gamma | polymer | 452 | 50304.2 | 2 | UniProt (Q9NR50) Pfam (PF00483) In PDB | Homo sapiens (Human) | eIF-2B GDP-GTP exchange factor subunit gamma |
Sequence modifications
A, B: 1 - 721 (UniProt: Q13144)
C, D: 2 - 351 (UniProt: P49770)
G, H: 2 - 305 (UniProt: Q14232)
PDB | External Database | Details |
---|---|---|
Val 587 | Ile 587 | conflict |
PDB | External Database | Details |
---|---|---|
Met -16 | - | initiating methionine |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Gly -9 | - | expression tag |
Gly -8 | - | expression tag |
Gly -7 | - | expression tag |
Ser -6 | - | expression tag |
Glu -5 | - | expression tag |
Asn -4 | - | expression tag |
Leu -3 | - | expression tag |
Tyr -2 | - | expression tag |
Phe -1 | - | expression tag |
Gln 0 | - | expression tag |
Ser 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -16 | - | initiating methionine |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Gly -9 | - | expression tag |
Gly -8 | - | expression tag |
Gly -7 | - | expression tag |
Ser -6 | - | expression tag |
Glu -5 | - | expression tag |
Asn -4 | - | expression tag |
Leu -3 | - | expression tag |
Tyr -2 | - | expression tag |
Phe -1 | - | expression tag |
Gln 0 | - | expression tag |
Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 530257.5 | |
All* | Total formula weight | 530257.5 |