7L6X
Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to GNE-371
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription initiation factor TFIID subunit 1 | polymer | 265 | 30968.3 | 1 | UniProt (P21675) Pfam (PF00439) | Homo sapiens (Human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250 |
| 2 | B (A) | 6-(but-3-en-1-yl)-4-[1-methyl-6-(morpholine-4-carbonyl)-1H-benzimidazol-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one | non-polymer | 431.5 | 1 | Chemie (G9V) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1373 - 1635 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Ser 1371 | - | expression tag |
| Met 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30968.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 555.6 | |
| All* | Total formula weight | 31523.9 |
