7L6V
Crystal structure of BoNT/A-LC-JPU-A5-JPU-C1-JPU-H7-JPU-D12-ciA-F12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BoNT/A | polymer | 425 | 48551.8 | 1 | UniProt (Q7B8V4) Pfam (PF01742) UniProt (by SIFTS) (P0DPI1) | Clostridium botulinum | BoNT/A1 neurotoxin,Bont/A1,Botulinum neurotoxin type A,Neurotoxin A,Neurotoxin BoNT,Neurotoxin type A,Peptidase M27 |
| 2 | B (B) | JPU-C1 | polymer | 122 | 13297.8 | 1 | Vicugna pacos (alpaca) | ||
| 3 | C (C) | JPU-A5 | polymer | 127 | 13674.3 | 1 | Vicugna pacos (alpaca) | ||
| 4 | D (D) | JPU-H7 | polymer | 122 | 13326.7 | 1 | Vicugna pacos (alpaca) | ||
| 5 | E (E) | Single-domain antibody VHH ciA-F12 | polymer | 125 | 13201.4 | 1 | Vicugna pacos (alpaca) | ||
| 6 | F (F) | JPU-D12 | polymer | 130 | 13747.2 | 1 | Vicugna pacos (alpaca) | ||
| 7 | G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 8 | I (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 9 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 520 | Chemie (HOH) |
Sequence modifications
A: 1 - 420 (UniProt: Q7B8V4)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 115799.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 189.5 | |
| All* | Total formula weight | 115988.7 |
