7L3P

Crystal Structure of Acetyl-CoA synthetase in complex with adenosine-5'-ethylphosphate and Co-enzyme A from Coccidioides immitis RS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Acetyl-coenzyme A synthetase	polymer	706	78435.8	1	UniProt (J3KJC6) Pfam (PF16177) Pfam (PF00501) Pfam (PF13193) In PDB	Coccidioides immitis (strain RS) (Valley fever fungus)
2	A	5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine	non-polymer		375.3	1	Chemie (WTA)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
4	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5		water	water		18.0	297	Chemie (HOH)

Sequence modifications

A: 1 - 691 (UniProt: J3KJC6)

PDB	External Database	Details
Met -15	-	initiating methionine
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	78435.8
Non-Polymers*	Number of molecules	10
	Total formula weight	967.9
All*	Total formula weight	79403.7

*Water molecules are not included.