7L35
Human DNA Ligase 1 - R771W nicked DNA complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA ligase 1 | polymer | 647 | 72057.3 | 1 | UniProt (P18858) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) In PDB | Homo sapiens (Human) | DNA ligase I,Polydeoxyribonucleotide synthase [ATP] 1 |
| 2 | B | DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3') | polymer | 11 | 3365.2 | 1 | Homo sapiens | ||
| 3 | C | DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3') | polymer | 7 | 2138.4 | 1 | Homo sapiens | ||
| 4 | D | DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3') | polymer | 18 | 5486.6 | 1 | Homo sapiens | ||
| 5 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | C | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 8 | D | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 9 | water | water | 18.0 | 605 | Chemie (HOH) |
Sequence modifications
A: 262 - 906 (UniProt: P18858)
| PDB | External Database | Details |
|---|---|---|
| Ser 260 | - | expression tag |
| Asn 261 | - | expression tag |
| Trp 771 | Arg 771 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83047.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 598.5 | |
| All* | Total formula weight | 83645.9 |
