7L2Y
HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Integrase | polymer | 162 | 17806.1 | 1 | UniProt (F2WR52) Pfam (PF00665) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | B, C, D, K (AAA) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | E, F, G, H, I (AAA) | IODIDE ION | non-polymer | 126.9 | 5 | Chemie (IOD) | |||
| 4 | J (AAA) | 4-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzoic acid | non-polymer | 334.3 | 1 | Chemie (XHY) | |||
| 5 | L (AAA) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
AAA: 50 - 212 (UniProt: F2WR52)
| PDB | External Database | Details |
|---|---|---|
| Glu 53 | Gln 53 | conflict |
| Ser 56 | Cys 56 | conflict |
| Glu 131 | Trp 131 | conflict |
| - | Met 154 | deletion |
| Lys 185 | Phe 185 | conflict |
| Glu 209 | Gln 209 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17806.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1353.1 | |
| All* | Total formula weight | 19159.2 |
