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7L2N

Cryo-EM structure of RTX-bound full-length TRPV1 in C1 state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, D, BTransient receptor potential cation channel subfamily V member 1polymer84295328.24UniProt (O35433)
Pfam (PF00023)
Pfam (PF00520)
In PDB
Rattus norvegicus (Rat)TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like
2A, C, D, Bresiniferatoxinnon-polymer628.74Chemie (6EU)
Sequence modifications
A, C, D, B: 2 - 838 (UniProt: O35433)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ala -2-expression tag
Met -1-expression tag
Gly 0-expression tag
Ser 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight381312.6
Non-Polymers*Number of molecules4
Total formula weight2514.8
All*Total formula weight383827.5
*Water molecules are not included.

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PDB entries from 2024-07-10

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