7L2L
Cryo-EM structure of RTX-bound full-length TRPV1 in O1 state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, D, B) | Transient receptor potential cation channel subfamily V member 1 | polymer | 842 | 95328.2 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Rat) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like |
| 2 | E, F, G, H (A, C, D, B) | resiniferatoxin | non-polymer | 628.7 | 4 | Chemie (6EU) PubChem (44564218) PubChem (53776296) PubChem (57090162) PubChem (2733497) PubChem (176519982) PubChem (104826) PubChem (71718531) PubChem (5311411) PubChem (5148108) PubChem (117893115) PubChem (124525003) PubChem (5702546) PubChem (6324660) PubChem (92845090) PubChem (134688669) PubChem (15814491) PubChem (171342682) PubChem (137635852) PubChem (139248250) |
Sequence modifications
A, C, D, B: 2 - 838 (UniProt: O35433)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 381312.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2514.8 | |
| All* | Total formula weight | 383827.5 |
