7L2H
Cryo-EM structure of unliganded full-length TRPV1 at neutral pH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, B, C) | Transient receptor potential cation channel subfamily V member 1 | polymer | 842 | 95328.2 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Rat) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like |
| 2 | E, H, J, L (A, D, B, C) | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate | non-polymer | 600.6 | 4 | Chemie (XJ7) | |||
| 3 | F, I, K, M (A, D, B, C) | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl tridecanoate | non-polymer | 523.6 | 4 | Chemie (XJD) | |||
| 4 | G (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) |
Sequence modifications
A, D, B, C: 2 - 838 (UniProt: O35433)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 381312.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 4520.1 | |
| All* | Total formula weight | 385832.7 |
