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7L1K

Cryo-EM structure of S. Pombe NatC complex with a Bisubstrate inhibitor and inositol hexaphosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
N-alpha-acetyltransferase 30polymer15017721.31UniProt (O74311)
Pfam (PF00583)
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)N-terminal acetyltransferase C complex catalytic subunit mak3 homolog,NatC catalytic subunit
2B
(B)
N-alpha-acetyltransferase 35, NatC auxiliary subunitpolymer70880541.31UniProt (Q9USY3)
Pfam (PF04112)
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)N-terminal acetyltransferase C complex subunit mak10,NatC complex subunit mak10
3C
(C)
N-alpha-acetyltransferase 38, NatC auxiliary subunitpolymer11613258.61UniProt (O43080)
Pfam (PF01423)
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)N-terminal acetyltransferase C complex subunit naa38
4D
(D)
MLGP peptidepolymer4416.51Homo sapiens
5E
(A)
INOSITOL HEXAKISPHOSPHATEnon-polymer660.01Chemie (IHP)
6F
(D)
CARBOXYMETHYL COENZYME *Anon-polymer825.61Chemie (CMC)
Sequence modifications
C: 1 - 116 (UniProt: O43080)
PDBExternal DatabaseDetails
Met 47Asn 47conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight111937.8
Non-Polymers*Number of molecules2
Total formula weight1485.6
All*Total formula weight113423.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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