7L1B
Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A alpha chain | polymer | 274 | 31628.8 | 1 | UniProt (P04439) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | Human leukocyte antigen A,HLA-A |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | wild-type PIK3CA peptide | polymer | 9 | 997.1 | 1 | UniProt (P42336) | Homo sapiens | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform,PtdIns-3-kinase subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,p110alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,Serine/threonine protein kinase PIK3CA |
| 4 | D, E (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F, G, H (A, B, C) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44505.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 44689.5 |
