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7L1B

Crystal structure of HLA-A*03:01 in complex with a wild-type PIK3CA peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHLA class I histocompatibility antigen, A alpha chainpolymer27431628.81UniProt (P04439)
Pfam (PF00129)
Pfam (PF07654)
In PDB
Homo sapiens (Human)Human leukocyte antigen A,HLA-A
2BBeta-2-microglobulinpolymer10011879.41UniProt (P61769)
Pfam (PF07654)
In PDB
Homo sapiens (Human)
3Cwild-type PIK3CA peptidepolymer9997.11UniProt (P42336)
In PDB
Homo sapiensPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform,PtdIns-3-kinase subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,p110alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,Serine/threonine protein kinase PIK3CA
4A, BGLYCEROLnon-polymer92.12Chemie (GOL)
5waterwater18.0289Chemie (HOH)
Sequence modifications
B: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight44505.3
Non-Polymers*Number of molecules2
Total formula weight184.2
All*Total formula weight44689.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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