7KZG
Human MBD4 glycosylase domain bound to DNA containing oxacarbenium-ion analog 1-aza-2'-deoxyribose
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Methyl-CpG-binding domain protein 4 | polymer | 174 | 20560.6 | 1 | UniProt (O95243) In PDB | Homo sapiens (Human) | Methyl-CpG-binding endonuclease 1,Methyl-CpG-binding protein MBD4,Mismatch-specific DNA N-glycosylase |
2 | C | DNA (5'-D(*CP*CP*AP*GP*CP*GP*(NR1)P*GP*CP*AP*GP*C)-3') | polymer | 12 | 3524.3 | 1 | Homo sapiens | ||
3 | D | DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3') | polymer | 12 | 3695.4 | 1 | Homo sapiens | ||
4 | A, C, D | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
5 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
7 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
8 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
9 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A: 426 - 580 (UniProt: O95243)
PDB | External Database | Details |
---|---|---|
Met 407 | - | expression tag |
Gly 408 | - | expression tag |
Ser 409 | - | expression tag |
Ser 410 | - | expression tag |
His 411 | - | expression tag |
His 412 | - | expression tag |
His 413 | - | expression tag |
His 414 | - | expression tag |
His 415 | - | expression tag |
His 416 | - | expression tag |
Ser 417 | - | expression tag |
Ser 418 | - | expression tag |
Gly 419 | - | expression tag |
Leu 420 | - | expression tag |
Val 421 | - | expression tag |
Pro 422 | - | expression tag |
Arg 423 | - | expression tag |
Gly 424 | - | expression tag |
Ser 425 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 27780.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 595.0 | |
All* | Total formula weight | 28375.3 |