7KZ2
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, Y110F mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site in C2221 space group
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34169.3 | 6 | UniProt (Q9PPB4) Pfam (PF00701) In PDB | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
2 | C, A, D, E, B... | LYSINE | non-polymer | 147.2 | 6 | Chemie (LYS) | |||
3 | C, A, E, B, F | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 13 | Chemie (PEG) | |||
4 | B, F, C, A, D... | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
5 | F, B, A | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
6 | F, B, C, D, A... | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 7 | Chemie (PGE) | |||
7 | B, C | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
8 | water | water | 18.0 | 1099 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)
PDB | External Database | Details |
---|---|---|
Met -11 | - | expression tag |
Arg -10 | - | expression tag |
Gly -9 | - | expression tag |
Ser -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Phe 110 | Tyr 110 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 205015.5 | |
Non-Polymers* | Number of molecules | 50 |
Total formula weight | 4678.2 | |
All* | Total formula weight | 209693.7 |