7KZ1
Human MBD4 glycosylase domain bound to DNA containing an abasic site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methyl-CpG-binding domain protein 4 | polymer | 157 | 18671.5 | 1 | UniProt (O95243) | Homo sapiens (Human) | Methyl-CpG-binding endonuclease 1,Methyl-CpG-binding protein MBD4,Mismatch-specific DNA N-glycosylase |
| 2 | B (C) | DNA (5'-D(*CP*CP*AP*GP*CP*GP*(ORP)P*GP*CP*AP*GP*C)-3') | polymer | 12 | 3540.3 | 1 | synthetic construct | ||
| 3 | C (D) | DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3') | polymer | 12 | 3695.4 | 1 | synthetic construct | ||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | F (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | G, H, I (A, C, D) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A: 426 - 580 (UniProt: O95243)
| PDB | External Database | Details |
|---|---|---|
| Gly 424 | - | expression tag |
| Ser 425 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 25907.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 177.2 | |
| All* | Total formula weight | 26084.3 |
