7KXH

Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site in C2221 space group

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34185.3	6	UniProt (Q9PPB4) Pfam (PF00701)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	G, LA, U (A, E, C)	(2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid	non-polymer		318.4	3	Chemie (3VN)
3	CA, DA, EA, H, I... (D, A, B, F, C)	MAGNESIUM ION	non-polymer		24.3	10	Chemie (MG)
4	FA, J, MA, N, SA... (D, A, E, B, F...)	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
5	GA, K, NA, O, P... (D, A, E, B, F...)	ACETATE ION	non-polymer		59.0	9	Chemie (ACT)
6	JA, KA, L, PA, YA (D, A, E, F)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	5	Chemie (PEG)
7	AA, BA, HA, IA, OA... (C, D, E, B, F)	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
8	AB, BB, CB, DB, EB... (B, C, D, E, F...)	water	water		18.0	849	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	205111.5
Non-Polymers*	Number of molecules	45
	Total formula weight	3906.1
All*	Total formula weight	209017.7

*Water molecules are not included.