7KXG

Dihydrodipicolinate synthase (DHDPS) from C.jejuni with pyruvate bound in the active site and L-histidine bound at the allosteric site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34185.3	6	UniProt (Q9PPB4) Pfam (PF00701)	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	AA, AB, BA, G, H... (C, F, A, D, B...)	MAGNESIUM ION	non-polymer		24.3	17	Chemie (MG)
3	BB, CA, I, LA, S... (F, C, A, D, B...)	TRIETHYLENE GLYCOL	non-polymer		150.2	7	Chemie (PGE)
4	CB, DA, J, MA, T (F, C, A, D, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	5	Chemie (PEG)
5	EA, EB, FA, FB, GB... (C, F, A, D, B...)	1,2-ETHANEDIOL	non-polymer		62.1	14	Chemie (EDO)
6	GA, HB, N, QA, XA... (C, F, A, D, E...)	HISTIDINE	non-polymer		156.2	6	Chemie (HIS)
7	DB, NA, U, UA, VA (F, D, B, E)	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)
8	IB (F)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
9	JB, KB, LB, MB, NB... (A, B, C, D, E...)	water	water		18.0	722	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	205111.5
Non-Polymers*	Number of molecules	55
	Total formula weight	4188.2
All*	Total formula weight	209299.8

*Water molecules are not included.