7KWF
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, F (A, B, F) | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34161.2 | 3 | UniProt (Q9PPB4) Pfam (PF00701) | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
| 2 | C, D, E (C, D, E) | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34092.2 | 3 | UniProt (Q9PPB4) Pfam (PF00701) | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
| 3 | G, I, L (B, C, E) | (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid | non-polymer | 318.4 | 3 | Chemie (3VN) | |||
| 4 | H, N (B, F) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | J, K (C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | M, O (E, F) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) |
Sequence modifications
A, B, F: 1 - 298 (UniProt: Q9PPB4)
C, D, E: 1 - 298 (UniProt: Q9PPB4)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 56 | His 56 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 56 | His 56 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 204760.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1585.9 | |
| All* | Total formula weight | 206346.1 |
