7KWF
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56N mutant with pyruvate bound in the active site and R,R-bislysine bound at the allosteric site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, F | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34161.2 | 3 | UniProt (Q9PPB4) Pfam (PF00701) In PDB | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
2 | C, D, E | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34092.2 | 3 | UniProt (Q9PPB4) Pfam (PF00701) In PDB | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
3 | B, C, E | (2R,5R)-2,5-diamino-2,5-bis(4-aminobutyl)hexanedioic acid | non-polymer | 318.4 | 3 | Chemie (3VN) | |||
4 | B, F | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
5 | C, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
6 | E, F | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) |
Sequence modifications
A, B, F: 1 - 298 (UniProt: Q9PPB4)
C, D, E: 1 - 298 (UniProt: Q9PPB4)
PDB | External Database | Details |
---|---|---|
Met -11 | - | expression tag |
Arg -10 | - | expression tag |
Gly -9 | - | expression tag |
Ser -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Asn 56 | His 56 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met -11 | - | expression tag |
Arg -10 | - | expression tag |
Gly -9 | - | expression tag |
Ser -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Asn 56 | His 56 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 204760.2 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1585.9 | |
All* | Total formula weight | 206346.1 |