7KWA
Structure of DCN1 bound to N-((4S,5S)-3-(aminomethyl)-7-ethyl-4-(4-fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-(trifluoromethyl)benzamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Endolysin,DCN1-like protein 1 | polymer | 384 | 44307.4 | 1 | UniProt (A0A097J809) UniProt (Q96GG9) Pfam (PF00959) Pfam (PF03556) In PDB | Enterobacteria phage RB59 | Lysis protein,Lysozyme,Muramidase,DCNL1,DCUN1 domain-containing protein 1,Defective in cullin neddylation protein 1-like protein 1,Squamous cell carcinoma-related oncogene |
2 | A | N-[(4S,5S)-3-(aminomethyl)-7-ethyl-4-(4-fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-(trifluoromethyl)benzamide | non-polymer | 551.5 | 1 | Chemie (YHP) | |||
3 | water | water | 18.0 | 378 | Chemie (HOH) |
Sequence modifications
A: 1 - 164 (UniProt: A0A097J809)
A: 1062 - 1259 (UniProt: Q96GG9)
PDB | External Database | Details |
---|---|---|
Met -21 | - | expression tag |
Gly -20 | - | expression tag |
Ser -19 | - | expression tag |
Ser -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
Ser -11 | - | expression tag |
Gln -10 | - | expression tag |
Asp -9 | - | expression tag |
Leu -8 | - | expression tag |
Glu -7 | - | expression tag |
Asn -6 | - | expression tag |
Leu -5 | - | expression tag |
Tyr -4 | - | expression tag |
Phe -3 | - | expression tag |
Gln -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Thr 54 | Cys 54 | conflict |
Ala 97 | Cys 97 | conflict |
Thr 146 | Ala 146 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 44307.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 551.5 | |
All* | Total formula weight | 44858.9 |