7KU6

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56N mutant with pyruvate bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34161.2	4	UniProt (Q9PPB4) Pfam (PF00701) In PDB	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	E, F	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34092.2	2	UniProt (Q9PPB4) Pfam (PF00701) In PDB	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
3	A, B, C, D, E...	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
4	A, B, D, F	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
5	A, D	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6		water	water		18.0	3	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 56	His 56	engineered mutation

E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 56	His 56	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	204829.2
Non-Polymers*	Number of molecules	13
	Total formula weight	1146.7
All*	Total formula weight	205975.9

*Water molecules are not included.