7KTF

DNA Polymerase Mu, 8-oxodGTP:Ct Product State Ternary Complex, 50 mM Mg2+ (180min)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA-directed DNA/RNA polymerase mu	polymer	356	40054.4	1	UniProt (Q9NP87) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) In PDB	Homo sapiens (Human)	Pol Mu,Terminal transferase
2	T	DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3')	polymer	9	2716.8	1		Homo sapiens
3	P	DNA (5'-D(*CP*GP*TP*AP*(8OG))-3')	polymer	5	1536.0	1		Homo sapiens
4	D	DNA (5'-D(P*GP*CP*CP*G)-3')	polymer	4	1191.8	1		Homo sapiens
5	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7	A	PYROPHOSPHATE	non-polymer		178.0	1	Chemie (PPV)
8	A, T	1,2-ETHANEDIOL	non-polymer		62.1	10	Chemie (EDO)
9	A	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
10		water	water		18.0	416	Chemie (HOH)

Sequence modifications

A: 132 - 494 (UniProt: Q9NP87)

PDB	External Database	Details
Gly 127	-	expression tag
Ser 128	-	expression tag
Ala 129	-	expression tag
Ala 130	-	expression tag
Ala 131	-	expression tag
Gly 410	Pro 398	linker
-	Gly 399	deletion
-	Ala 400	deletion
-	Ala 401	deletion
-	Val 402	deletion
-	Gly 403	deletion
-	Gly 404	deletion
-	Ser 405	deletion
-	Thr 406	deletion
-	Arg 407	deletion
-	Pro 408	deletion
-	Cys 409	deletion
-	Pro 410	deletion

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	45499.1
Non-Polymers*	Number of molecules	15
	Total formula weight	1108.6
All*	Total formula weight	46607.6

*Water molecules are not included.