7KRN

Structure of SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase	polymer	932	106781.0	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	Pol,RdRp,Non-structural protein 12,nsp12
2	B, D	Non-structural protein 8	polymer	199	22034.2	2	UniProt (P0DTD1) Pfam (PF08717) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	nsp8
3	C	Non-structural protein 7	polymer	88	9748.4	1	UniProt (P0DTD1) Pfam (PF08716) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	nsp7
4	E	Helicase	polymer	605	67354.0	1	UniProt (P0DTD1) Pfam (PF20632) Pfam (PF20633) Pfam (PF20631) Pfam (PF13087) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	Hel,Non-structural protein 13,nsp13
5	P	RNA (37-MER)	polymer	40	12667.6	1		Severe acute respiratory syndrome coronavirus 2
6	T	RNA (43-MER)	polymer	55	17573.4	1		Severe acute respiratory syndrome coronavirus 2
7	A, E	ZINC ION	non-polymer		65.4	5	Chemie (ZN)
8	A, E	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
9	A, E	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
10	A, E	CHAPSO	non-polymer		631.9	3	Chemie (1N7)
11	E	ALUMINUM FLUORIDE	non-polymer		84.0	1	Chemie (AF3)

Sequence modifications

B, D: 1 - 198 (UniProt: P0DTD1)

PDB	External Database	Details
Met 0	-	initiating methionine

C: 1 - 83 (UniProt: P0DTD1)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Val -2	-	expression tag
Asp -1	-	expression tag
Met 0	-	expression tag

E: 1 - 601 (UniProt: P0DTD1)

PDB	External Database	Details
Gly -3	-	expression tag
Pro -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	258192.8
Non-Polymers*	Number of molecules	13
	Total formula weight	3209.7
All*	Total formula weight	261402.5

*Water molecules are not included.