7KRI

FR6-bound SARS-CoV-2 Nsp9 RNA-replicase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Non-structural protein 9	polymer	133	14592.6	3	UniProt (P0DTD1) Pfam (PF08710)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	nsp9
2	D, G, J (A, B, C)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	E, F, H, I, L... (A, B, C)	1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione	non-polymer		179.2	6	Chemie (X0Y)
4	K (C)	MALONATE ION	non-polymer		102.0	1	Chemie (MLI)
5	N, O, P (A, B, C)	water	water		18.0	314	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 113 (UniProt: P0DTD1)

PDB	External Database	Details
Met -19	-	initiating methionine
Ala -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ala -10	-	expression tag
Ala -9	-	expression tag
Leu -8	-	expression tag
Glu -7	-	expression tag
Val -6	-	expression tag
Leu -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Gly -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	43777.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1465.3
All*	Total formula weight	45243.2

*Water molecules are not included.