7KR8

Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H56A mutant with pyruvate bound in the active site

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	4-hydroxy-tetrahydrodipicolinate synthase	polymer	310	34118.2	6	UniProt (Q9PPB4) Pfam (PF00701) In PDB	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	HTPA synthase
2	D, A, B, E, F...	1,2-ETHANEDIOL	non-polymer		62.1	11	Chemie (EDO)
3	D, A, B, F, C	TRIETHYLENE GLYCOL	non-polymer		150.2	7	Chemie (PGE)
4	D, A, E, B, C	ACETATE ION	non-polymer		59.0	9	Chemie (ACT)
5	D, E, B, C	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG)
6	D, B, F, C	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	5	Chemie (PEG)
7		water	water		18.0	1004	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 56	His 56	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	204709.1
Non-Polymers*	Number of molecules	39
	Total formula weight	2966.1
All*	Total formula weight	207675.2

*Water molecules are not included.