7KQR

A 1.89-A resolution substrate-bound crystal structure of heme-dependent tyrosine hydroxylase from S. sclerotialus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heme-dependent L-tyrosine hydroxylase	polymer	316	34623.1	2		Streptomyces sclerotialus
2	C, H (A, B)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	D, I (A, B)	TYROSINE	non-polymer		181.2	2	Chemie (TYR)
4	E (A)	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
5	F, G (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
6	J, K (A, B)	water	water		18.0	424	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69246.2
Non-Polymers*	Number of molecules	7
	Total formula weight	2048.9
All*	Total formula weight	71295.1

*Water molecules are not included.