7KNW

Crystal structure of SND1 in complex with C-26-A2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Staphylococcal nuclease domain-containing protein 1	polymer	324	36797.0	4	UniProt (Q7KZF4) Pfam (PF00565)	Homo sapiens (Human)	100 kDa coactivator,EBNA2 coactivator p100,Tudor domain-containing protein 11,p100 co-activator
2	E, G, J (A, B, D)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
3	F, H, I, K (A, B, C, D)	5-chloro-2-methoxy-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide	non-polymer		338.8	4	Chemie (QOY)
4	L, M, N, O (A, B, C, D)	water	water		18.0	421	Chemie (HOH)

Sequence modifications

A, B, C, D: 16 - 330 (UniProt: Q7KZF4)

PDB	External Database	Details
Met -4	-	initiating methionine
Gly -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
Ser 6	-	expression tag
Ser 7	-	expression tag
Gly 8	-	expression tag
Glu 9	-	expression tag
Asn 10	-	expression tag
Leu 11	-	expression tag
Tyr 12	-	expression tag
Phe 13	-	expression tag
Gln 14	-	expression tag
Gly 15	-	expression tag
-	Ala 64	deletion
-	Ala 65	deletion
-	Thr 66	deletion
-	Gln 67	deletion
-	Pro 68	deletion
-	Asp 69	deletion
-	Glu 234	deletion
-	Ala 235	deletion
-	Asp 236	deletion
-	Gly 237	deletion
-	Ser 238	deletion

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	147188.0
Non-Polymers*	Number of molecules	7
	Total formula weight	1631.4
All*	Total formula weight	148819.3

*Water molecules are not included.